Professor in Healthcare Systems and a Professor Fellow in Internal Medicine at the Tel Aviv University.
For the past thirty three years served as the Director of the Chaim Sheba Medical Center, until retiring from public service, and he has served twice as the Director of the Ministry of Health (1979 and 1993-1994).
Also served as a member of a Committee of Inquiry (headed by Judge Netanyahu) that investigated the healthcare system, and whose recommendations led to legislature of the Healthcare Law, which he implemented during his second tenure as Director of the Ministry of Health.
The Chairman of the Management Committee of the Gertner Institute for Epidemiology and Health Policy Research.
Founded in 2005 the School of Public Health at the Tel Aviv University, and was the head till 2009.
In 2009 received the Israel prize for Lifetime Achievement. The prize was awarded "for a lifetime of exemplary public service, and for being the guiding light and father figure for medicine and the health system of Israel."